RheumaView™ · Case Study · Longitudinal

The Same X-Rays, Read Two Ways

A conventional radiology report beside a RheumaView™ structured longitudinal report — one peripheral dataset, two timepoints, read for structural stability rather than dramatic damage.


De-identified case · Female · 22 Baseline 2025 Follow-up 2026 · ~14-month interval Modality: Radiograph Regions: Hands/wrists + feet/ankles
Complexity: Longitudinal · 2 timepoints (~14 mo) · Radiograph · single-modality
Why this is a representative longitudinal case

This is a low-damage early case: there is no erosive transformation and no interval progression, so it is not a “dramatic findings” showcase. Its value is the opposite — showing how a structured report frames stability over time, keeps subtle degenerative/mechanical background separate from inflammatory interpretation, and flags an honest data limitation (the follow-up hand series is richer than baseline). See how case complexity scales →

What a typical report says
Conventional · per-region · qualitative
ExamBilateral hands/wrists and bilateral feet/ankles, multiple views
HistoryPolyarthralgia.
ComparisonLimited.
Hands and wrists

The visualized osseous structures are intact, with no acute fracture or dislocation. Bony mineralization appears within normal limits. The carpal and metacarpophalangeal joint spaces are grossly maintained. No aggressive osseous lesion is identified. The overlying soft tissues are unremarkable.

Feet and ankles

No acute fracture or dislocation is seen. There is mild bilateral hallux valgus. No aggressive osseous lesion is identified. The visualized joint spaces are grossly preserved and the ankle mortises appear maintained. The remainder of the examination is unremarkable.

Impression

1. No significant acute osseous abnormality of the hands, wrists, feet or ankles.

2. Mild bilateral hallux valgus.

RheumaView™ structured report
Structured · graded · longitudinal · depth-tiered
TierREADY+ · Gold Standard
CaseRheumaView™ demo case
PatientDe-identified · Female · 22
StudyFollow-up 2026; comparison 2025 (~14-month interval)
ExamBilateral hands/wrists and bilateral feet/ankles radiographs
Projections2026: right hand PA/oblique/lateral plus dedicated wrist views; left hand PA/oblique/lateral plus dedicated wrist views; bilateral ball-catcher/clenched-type hand views; bilateral feet AP/oblique/lateral; bilateral frontal ankles.
2025: bilateral hands PA/oblique; bilateral feet AP/oblique/lateral; bilateral frontal ankles.
AdequacyLongitudinal comparison is somewhat stronger for feet/ankles than for hands/wrists because the follow-up study includes additional hand/wrist projections not present at baseline. Comparison remains adequate for structural assessment.
Findings — hands / wrists

No acute osseous abnormality. Alignment preserved bilaterally. Bone mineralization maintained without convincing periarticular osteopenia. MCP, PIP and DIP joint spaces preserved bilaterally without convincing inflammatory joint-space narrowing. Radiocarpal, intercarpal and visualized carpometacarpal relationships preserved.

No definite marginal erosions in either hand or wrist on baseline or follow-up. No convincing periostitis, acro-osteolysis, carpal collapse or inflammatory proliferative bone formation.

On follow-up, very mild scattered non-erosive interphalangeal contour irregularity / marginal spurring, most conspicuous at a few DIP joints and the thumb IP joint, low-grade degenerative in appearance — subtle, not associated with erosive change. No definite inflammatory interval change.

Findings — right foot / ankle

Mild hallux valgus with mild medial first-metatarsal-head prominence / bunion-type morphology. First MTP joint space preserved to minimally narrowed, without erosive change. Lesser MTP and IP joint spaces preserved. Midfoot alignment maintained. No focal erosions, periostitis or inflammatory proliferative change. Ankle mortise/alignment preserved; no tibiotalar erosive change.

Compared with baseline (2025): no convincing interval structural progression.

Findings — left foot / ankle

Mild hallux valgus with mild medial first-metatarsal-head prominence / bunion-type morphology. First MTP joint space preserved to minimally narrowed, without erosive change. Lesser forefoot joint spaces preserved. Midfoot alignment maintained. Tiny plantar calcaneal enthesopathic spur present. No convincing erosive change in forefoot, midfoot or ankle; mortise/alignment preserved.

Compared with baseline (2025): no convincing interval structural progression; tiny plantar calcaneal spur stable.

Impression
  1. No definite radiographic evidence of erosive inflammatory arthritis in the imaged hands, wrists, feet or ankles.
  2. No convincing radiographic progression between the 2025 baseline and 2026 follow-up.
  3. Mild bilateral hallux valgus / bunion-type morphology.
  4. Very subtle scattered non-erosive interphalangeal degenerative-type irregularity/spurring, best seen on the follow-up hand series, without erosive features.
  5. Stable tiny left plantar calcaneal enthesopathic spur.
EMR summary

Longitudinal peripheral radiographs from 2025 and 2026 show no radiographic joint damage from RA. No erosions, inflammatory joint-space loss, periostitis or other destructive inflammatory changes are identified in the hands/wrists or feet/ankles, and there is no convincing interval progression over this ~14-month period. Mild incidental noninflammatory findings include bilateral mild hallux valgus/bunion-type morphology, very subtle scattered non-erosive interphalangeal degenerative-type spurring, and a stable tiny left plantar calcaneal spur. Overall imaging remains most consistent with a non-erosive, structurally stable peripheral study. Pattern tags: non-erosive / no radiographic RA damage / mild incidental mechanical-degenerative findings. Progression tag: stable / no structural progression.

What changes structurally between the two reports
structuredper-joint gradingpattern separationmimic-controllaterality quantifiedlongitudinal baselineincidental capturedata-needsoutput-depth tiers
Architectural differences only — the side-by-side speaks for itself.
Imaging — baseline (2025)
DEMO. Click any image to enlarge. These are reduced-resolution de-identified demonstration images; full-resolution individual radiographs are available on request. The full same-date sets are also in the attached 2025 PDF (button).
↗ Larger images — attached 2025 PDF (demo)
Imaging — follow-up (2026)
DEMO. Click any image to enlarge. Reduced-resolution de-identified demonstration images; full-resolution on request (full same-date set also in the attached 2026 PDF). Follow-up adds dedicated wrist, functional and ball-catcher hand projections not present at baseline (noted in adequacy).
↗ Larger images — attached 2026 PDF (demo)
Research / analytics addendum
Excerpt · image-derived semiquantitative · not formal central-read scores
A · Quantitative radiologic measures
Region-level structural scores
Region2025 Erosion2025 JSN2025 Total2026 Erosion2026 JSN2026 TotalInterval Δ
Right hand/wrist0000000
Left hand/wrist0000000
Right forefoot0000000
Left forefoot0000000
Combined peripheral inflammatory damage0000000
Region-level structural burden classes
Region2025 Class2026 ClassComment
Hands/wristsNoneNoneNo erosive or inflammatory narrowing burden detected
ForefeetNoneNoneNo erosive or inflammatory narrowing burden detected
AnklesNoneNoneNo structural inflammatory burden detected
Incidental noninflammatoryMildMildMild bilateral hallux valgus/bunion; tiny stable left plantar heel spur; very subtle non-erosive IP spurring on follow-up
Joint-level targeted checkpoints
Joint set20252026Interval
MCP 1–5 bilaterallyPreserved; no erosionsPreserved; no erosionsStable
PIP 2–5 bilaterallyPreserved; no erosionsPreserved; no erosionsStable
DIP 2–5 bilaterallyPreservedPreserved; trace non-erosive contour irregularity/spurring at a few jointsMinimal noninflammatory visible detail increase, no destructive change
Radiocarpal/intercarpal jointsPreservedPreservedStable
First MTP joints bilaterallyPreservedPreserved to minimally narrowed, non-erosiveStable to minimal noninflammatory remodeling
Lesser MTP joints bilaterallyPreservedPreservedStable
Tibiotalar joints bilaterallyPreservedPreservedStable
B · Longitudinal & temporal metrics
Delta matrix
MetricR hand/wristL hand/wristR foot/ankleL foot/ankleGlobal Peripheral
Erosion delta00000
Inflammatory JSN delta00000
Osteophyte / spur delta00000
Alignment delta00000
Enthesopathic delta00000
Composite inflammatory progression delta00000
Temporal stability summary
DomainScore (0–1)Class
Hands/wrists structural stability0.98Very high stability
Feet/ankles structural stability0.97Very high stability
Global peripheral structural stability0.98Very high stability
Directional drift vectors
DomainVector
Inflammatory damage driftNeutral
Degenerative/mechanical driftMinimal
Alignment driftNeutral
Enthesopathic driftNeutral
C · Age-adjusted reference values
Age-adjusted reference envelope
RegionAge-expected structural envelopeObserved position
Hands/wristsExpected to be structurally normal at age 22Within expected range
Feet/anklesExpected to be structurally normal at age 22Within expected range
First ray / bunion morphologyMild variation can be present in healthy young adultsMild bilateral hallux valgus/bunion morphology, still low-burden
Plantar heel enthesisSpur formation uncommon but may occur as incidental low-grade findingTiny unilateral left plantar spur; low-burden outlier but clinically minor by imaging
Age-adjusted structural burden estimate
Measure20252026
Age-adjusted inflammatory burden0.000.00
Age-adjusted noninflammatory burden0.080.10
Age-adjusted total structural burden0.080.10
D · Symmetry & balance metrics
Symmetry & balance
Symmetry domain2025 (0–1)2026 (0–1)Pattern
Hand symmetry0.990.97Near-symmetric
Wrist symmetry1.000.99Symmetric
Forefoot symmetry0.950.94Mild bilateral matched first-ray valgus morphology
Ankle symmetry1.001.00Symmetric
Global peripheral symmetry0.980.97Near-symmetric
Side-difference matrix
Region pairMain side difference
Right vs left handsTrace additional visible non-erosive IP contour irregularity on follow-up, low magnitude
Right vs left wristsNo meaningful asymmetry
Right vs left forefeetMild bilateral hallux valgus on both sides; no meaningful destructive asymmetry
Right vs left hindfoot/anklesTiny left plantar heel spur; otherwise no meaningful asymmetry
E · Bone-health / densitometric correlation summary

No densitometry dataset was provided for this case. Cross-modality bone-density linkage is therefore not computed.

MeasureStatus
Bone-density linkage availabilityNot available
Bone-quality alignment estimateNot computed
Multiregion densitometric coherenceNot computed
F · Composite structural metrics
Composite structural metrics
Composite metric20252026Interpretation
Composite Structural Stability Index0.980.98Highly stable
Structure Trajectory ClassStable normal / low-burden incidentalStable normal / low-burden incidentalNo inflammatory trajectory signal
Composite Discrepancy ClassMinimalMinimalClinical and imaging burden remain low
Regional Composite Burden Score0.040.06Very low total burden
Inflammatory Structural Risk Surface0.020.03Very low
Mechanical / incidental structural surface0.100.12Mild
Phenotype balance profile
AxisOutput
Inflammatory-destructive axisAbsent radiographically
Mechanical/incidental axisMild
Symmetry axisHigh bilateral balance
Longitudinal progression axisStable
Early-disease preservation axisStrongly preserved structure
G · QA / reliability indicators
QA / reliability indicators
IndicatorValueComment
Source completeness1.00All available declared projections reviewed
Comparison integrity0.96Longitudinal comparison adequate; follow-up hand set richer than baseline
View-to-region matching confidence0.99High
Descriptor completeness index0.98High
Concordance index0.95High internal agreement
Confidence-weighted summary score0.94High
Missingness burden0.04Mild, driven by unequal hand projection richness between time points
Reliability notes
  • Longitudinal confidence is highest for feet/ankles and preserved for hands/wrists.
  • Follow-up hand series contains added projections; this increases sensitivity for subtle non-destructive detail on follow-up without demonstrating true destructive progression.
  • No destructive inflammatory mismatch signal identified across the serial studies.
Experimental Research Addendum
A · Prototype composite metrics
Prototype metric20252026Comment
Exploratory Stability Curve0.970.98Flat-to-stable trajectory
Alternate Discrepancy Map0.050.06Very low mismatch burden
Low-Burden Preservation Vector0.990.99Strong preservation of native structure
B · Extended bone-health models

No external bone-health dataset was attached. Extended bone-health vectors are limited to radiograph-only inference.

Model outputStatus
Investigational bone-quality vectorLow concern by radiograph-only morphology
Enhanced mineralization coherence estimatePreserved
Extended bone-health linkageNot computed beyond radiograph-only inference
C · Advanced safety operators
OperatorOutput
Infection-pattern vectorNo concerning structural signal
Destructive-lesion vectorNo concerning structural signal
Therapy-response structural signatureStable preserved peripheral structure under interval treatment context
D · Advanced symmetry maps
MapOutput
Higher-order hand asymmetry surfaceMinimal
Higher-order forefoot asymmetry surfaceMild, bilateral first-ray morphology dominant
Global asymmetry heat profileLow-intensity focal left plantar hindfoot asymmetry only
E · Developmental / maturity modulation
FieldOutput
Skeletal maturity stateMature pattern
Developmental confounder burdenNone identified radiographically
Congenital/developmental structural overlayNo meaningful developmental distortion of interpretation
F · External integration hooks
FieldOutput
External model linkageNot supplied
Manual override provenanceNone required from current image set
Cross-system research export readinessCompatible
G · QA & data integrity extensions
ExtensionValueComment
Projection imbalance flagPresentFollow-up hand/wrist series richer than baseline
Region missingness counter0No declared region missing
Timepoint integrity1.00Two complete peripheral timepoints available
Experimental data integrity score0.95High
Structured analytic summary

This serial peripheral dataset demonstrates a non-erosive, structurally stable profile with zero quantified inflammatory damage at both time points and zero interval destructive progression. The visible burden is confined to mild bilateral first-ray valgus/bunion morphology, trace non-erosive interphalangeal spurring on follow-up, and a stable tiny left plantar heel spur. Age-adjusted burden remains very low, symmetry remains high, and the temporal stability profile is strongly preserved. No radiographic signal of evolving erosive rheumatoid damage is identified on the available studies.

RheumaView™ is a physician-curated reporting assistant and not an FDA-approved diagnostic device. Outputs support clinical decision-making; the treating physician retains full responsibility. Methods reference validated scoring systems and internal QA metrics as defined in the Master Protocol and annexed specifications.

How case complexity scales

The same architecture renders at controllable depth as a case gets harder. Each tier contributes and compounds; this is not a statement about accuracy.

Foundational
Single-date · one modality

A single timepoint read in depth — full descriptor coverage, per-joint grading and mimic-control on one study.

LongitudinalThis case
Multi-date · interval comparison

Two or more timepoints compared on a shared structural frame; interval deltas and stability are made explicit. Coverage compounds across dates.

Multi-modality
>1 modality

Radiograph combined with US / MRI / DEXA; cross-modality coverage adds activity and bone-density dimensions the radiograph alone cannot carry.

RheumaView™ structured report — depth tiers
Full-resolution de-identified image sets
De-identified educational/research demonstration. Not medical advice and not an FDA-approved diagnostic device. Reports shown are physician-curated structured outputs; clinical decisions remain with the treating physician.