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RV-006 · SP-PER

Olga Goodman, MD

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RheumaView™ · RV-006 · SP-PER

Detection Is Just the Beginning

The same bilateral knee radiographs, read two ways — a conventional report beside a RheumaView™ structured radiographic report.

De-identified caseFemaleAge 84Baseline 2026RadiographBilateral knees
Complexity: Foundational · Single-date · Radiograph · Single-modality
Why this is a foundational, representative case

This case sits at the entry tier of the complexity ladder: a single study date, a single modality (radiographs), and one paired region (both knees). It is “representative” rather than maximal — there is no prior for interval comparison, no DEXA, and no cross-modality fusion. What it shows is the architecture on a clean foundational example: per-compartment structural read, separation of a post-traumatic pattern from age-related primary osteoarthritis, quantified left-right asymmetry, and explicit data-needs. See how case complexity scales ↗

Clinical vignette

An 84-year-old woman was referred to rheumatology for management of presumed “arthritis,” with progressive pain and deformity following prior trauma and surgery.

Conventional

What a typical report says

DEPARTMENT OF RADIOLOGY
EXAMBilateral knees, multiple views (AP standing, PA flexion weight-bearing, oblique and lateral views)
DATE OF SERVICE2026-xx-xx
PATIENTDe-identified — Female — DOB 1941-xx-xx (Age 84)
INDICATIONKnee pain.
COMPARISONNone available.
FINDINGS

Right knee: Postsurgical changes are present, with a plate and multiple screws fixating the proximal tibia. The hardware appears intact without definite evidence of fracture or loosening. There is deformity of the proximal tibia. Degenerative changes are noted with joint space narrowing, osteophyte formation, and subchondral sclerosis. No acute fracture or dislocation. No joint effusion identified. Soft tissues are unremarkable.

Left knee: No fracture or dislocation. Mild to moderate degenerative changes with joint space narrowing and marginal osteophytes. No significant joint effusion. No radiopaque foreign body. Soft tissues are unremarkable.

IMPRESSION
  1. Postsurgical changes of the right knee with plate-and-screw fixation of the proximal tibia, intact. Associated osseous deformity.
  2. Degenerative changes of the right knee.
  3. Mild to moderate degenerative changes of the left knee.
  4. No acute fracture or dislocation.

Electronically signed.

RheumaView™ structured

RheumaView™ structured radiographic report

Same dataset, three rendering depths — depth selectable, structure preserved.

STUDY DATE2026-xx-xx
PATIENTDe-identified Sex: Female DOB: 1941-xx-xx (Age 84)
DECLARED / EXAMINED REGIONSBilateral knees
VIEWSBilateral knees: AP standing, PA flexion. Right knee: AP, oblique, lateral. Left knee: AP, oblique, lateral
PROJECTION ADEQUACYOverall diagnostic. Fixation hardware partially overlies the proximal right tibia, but joint spaces, articular contours, hardware integrity, and compartmental degenerative changes are adequately visualized.
FINDINGS

Right knee: Chronic healed fracture deformity of the proximal tibia/tibial plateau with lateral plate-and-screw fixation. Hardware is intact without visible breakage or definite perihardware lucency to suggest loosening on the provided projections. There is chronic deformity and irregularity of the lateral tibial plateau articular surface with persistent joint line incongruity/step-off.

The lateral tibiofemoral compartment demonstrates near-complete joint space loss with marked subchondral sclerosis and marginal osteophytes, consistent with severe lateral-predominant post-traumatic osteoarthritis. The medial tibiofemoral compartment shows mild to moderate joint space narrowing with lesser osteophyte formation and mild subchondral sclerosis. Mild patellofemoral degenerative change is present without advanced patellofemoral collapse.

No acute fracture, dislocation, or focal destructive osseous lesion is identified. Small joint effusion cannot be excluded on the lateral view.

Left knee: Mild medial tibiofemoral joint space narrowing with small marginal osteophytes, compatible with mild medial-predominant osteoarthritis. Lateral tibiofemoral joint space is preserved. Patellofemoral compartment is relatively preserved without significant degenerative narrowing. No acute fracture, dislocation, or focal destructive osseous lesion is identified. Small posterior ossicle is present, compatible with a fabella.

Bone quality: Generalized decreased mineralization of the visualized osseous structures, compatible with osteopenic change.

COMPARISON

No comparison studies available.

IMPRESSION
  1. Bilateral knees with markedly asymmetric degenerative pattern, dominated by severe right lateral-predominant post-traumatic osteoarthritis in the setting of chronic healed proximal tibial/tibial plateau fracture deformity and intact lateral fixation hardware.
  2. Additional mild to moderate right medial and mild right patellofemoral degenerative change.
  3. Mild left medial-predominant osteoarthritis with preservation of the left lateral and largely preserved left patellofemoral compartments.
  4. No acute osseous abnormality identified on the current study.
  5. Structural severity is disproportionately advanced in the right knee relative to age alone because of chronic post-traumatic articular remodeling; left-sided changes are within expected late-life mild degenerative range.
  6. Confidence: high for severe right lateral compartment post-traumatic degenerative change and hardware integrity; moderate for small effusion assessment and osteopenic appearance.
EMR SUMMARY

Pattern: markedly asymmetric bilateral knee osteoarthritis, severe on the right and mild on the left; right knee is lateral-predominant and post-traumatic in distribution. Progression: no prior knee radiographs available for interval comparison. Inflammatory features: no radiographic erosive inflammatory arthropathy identified. DISH: not applicable on this examination. Fracture: chronic healed proximal tibial/tibial plateau fracture deformity with residual articular incongruity and intact fixation hardware.

STUDY DATE2026-xx-xx
PATIENTDe-identified Sex: Female DOB: 1941-xx-xx (Age 84)
DECLARED / EXAMINED REGIONSBilateral knees
VIEWSBilateral knees: AP standing, PA flexion. Right knee: AP, oblique, lateral. Left knee: AP, oblique, lateral
PROJECTION ADEQUACYOverall diagnostic. Fixation hardware partially overlies the proximal right tibia, but joint spaces, articular contours, and hardware integrity are adequately visualized.
FINDINGS

Right knee: Chronic healed fracture deformity of the proximal tibia/tibial plateau with lateral plate-and-screw fixation. Hardware is intact without visible breakage or definite radiographic loosening on the provided projections. There is chronic deformity and irregularity of the lateral tibial plateau articular surface with persistent joint line incongruity/step-off.

The lateral tibiofemoral compartment demonstrates near-complete joint space loss with marked subchondral sclerosis and marginal osteophyte formation, consistent with severe lateral-predominant post-traumatic osteoarthritis. The medial tibiofemoral compartment shows mild to moderate joint space narrowing with lesser osteophyte formation and mild subchondral sclerosis. Mild patellofemoral degenerative change is present. Overall coronal alignment is preserved on standing views without gross varus or valgus subluxation.

No acute fracture, dislocation, or focal destructive osseous lesion is identified. Small joint effusion cannot be excluded on the lateral view.

Left knee: Mild medial tibiofemoral joint space narrowing with small marginal osteophytes, compatible with mild medial-predominant osteoarthritis. The lateral tibiofemoral compartment is preserved. The patellofemoral compartment is relatively preserved without significant degenerative narrowing. No acute fracture, dislocation, or focal destructive osseous lesion is identified. Small posterior ossicle is present, compatible with a fabella.

Bone quality: Generalized decreased mineralization of the visualized osseous structures, compatible with osteopenic change.

COMPARISON

No comparison studies available.

IMPRESSION
  1. Markedly asymmetric bilateral knee degenerative disease, dominated by severe right lateral-predominant post-traumatic osteoarthritis in the setting of chronic healed proximal tibial/tibial plateau fracture deformity with persistent articular incongruity and intact lateral fixation hardware.
  2. Additional mild to moderate right medial and mild right patellofemoral degenerative change.
  3. Mild left medial-predominant osteoarthritis with preservation of the left lateral and largely preserved left patellofemoral compartments.
  4. No acute osseous abnormality identified on the current study.
  5. Structural severity in the right knee is disproportionately advanced for age alone and is primarily trauma-driven; left-sided changes are within expected mild late-life degenerative range.
  6. Confidence is high for the major right post-traumatic degenerative findings and hardware integrity, and moderate for small effusion assessment and osteopenic appearance.
STUDY DATE2026-xx-xx
PATIENTDe-identified Sex: Female DOB: 1941-xx-xx (Age 84)
DECLARED / EXAMINED REGIONSBilateral knees
VIEWSBilateral knees: AP standing, PA flexion. Right knee: AP, oblique, lateral. Left knee: AP, oblique, lateral
PROJECTION ADEQUACYOverall diagnostic. Fixation hardware partially overlies the proximal right tibia, but joint spaces, articular contours, and hardware integrity are adequately visualized.
FINDINGS

Right knee

  • Chronic healed proximal tibial/tibial plateau fracture deformity with lateral plate-and-screw fixation.
  • Hardware intact; no visible breakage or definite radiographic loosening.
  • Chronic lateral tibial plateau articular irregularity with persistent joint line incongruity/step-off.
  • Severe lateral tibiofemoral joint space loss with marked subchondral sclerosis and marginal osteophytes; severe lateral-predominant post-traumatic osteoarthritis.
  • Mild to moderate medial tibiofemoral joint space narrowing with lesser osteophytes and mild subchondral sclerosis.
  • Mild patellofemoral degenerative change.
  • No acute fracture, dislocation, or focal destructive osseous lesion.
  • Small joint effusion not excluded on lateral view.

Left knee

  • Mild medial tibiofemoral joint space narrowing with small marginal osteophytes; mild medial-predominant osteoarthritis.
  • Lateral tibiofemoral compartment preserved.
  • Patellofemoral compartment relatively preserved.
  • No acute fracture, dislocation, or focal destructive osseous lesion.
  • Small posterior ossicle compatible with fabella.

Bone quality

  • Generalized decreased mineralization; osteopenic appearance.
COMPARISON

No comparison studies available.

IMPRESSION
  • Pattern: markedly asymmetric bilateral knee degenerative disease, dominated by severe right lateral-predominant post-traumatic osteoarthritis with chronic healed proximal tibial/tibial plateau fracture deformity and intact fixation hardware; mild left medial-predominant osteoarthritis.
  • Confidence: high for major right post-traumatic degenerative findings and hardware integrity; moderate for small effusion assessment and osteopenic appearance.
  • Progression: no prior knee radiographs available for interval comparison.
  • Age-context: right knee structural severity is disproportionately advanced for age and trauma-dominant; left knee changes are within expected mild late-life degenerative range.
What is structurally different
Structured outputPer-compartment grading (JSN / sclerosis / osteophyte)Pattern separation: post-traumatic vs primary OALaterality quantified (R:L burden ratios)Bilateral symmetry analyticsMimic-control: infection / oncologic screenIncidental capture (fabella, osteopenic background)Explicit data-needs (DEXA, priors)Output-depth tiersLongitudinal baseline anchor

Research / Analytics Addendum

Excerpt — image-derived semiquantitative; not formal central-read scores
STUDY DATE 2026-xx-xx
PATIENT De-identified · Sex: Female · DOB: 1941-xx-xx (Age 84)

1. Dataset scope and computation context

ParameterValue
ModalityXR only
Region setBilateral knees
Views usedBilateral AP standing, bilateral PA flexion, right AP, right oblique, right lateral, left AP, left oblique, left lateral
Timepoint statusSingle timepoint / baseline only
Prior matched studyNone available
DEXA attachedNo
Cross-modality fusionNot activated
Arthroplasty exclusionNo arthroplasty present
Hardware contextPost-traumatic fixation hardware present in right proximal tibia
Analytic basisXR-derived structural extraction with research-tier estimations where applicable
Confidence framingRadiograph-based quantitative estimates; exact submillimetric and densitometric values are not directly measurable from the current dataset

2. Quantitative Radiologic Measures

2A. Compartment-level structural scoring

Scale references used in this addendum

  • JSN: 0 none, 1 mild, 2 definite/moderate, 3 severe / near-complete, 4 complete loss
  • Osteophytes / sclerosis / deformity: 0 none to 3 marked
  • Structural burden: 0-4 composite regional burden
  • KL: 0-4
  • Ahlbäck: 0-5
Region / compartmentJSN (0-4)Osteophytes (0-3)Sclerosis (0-3)Articular deformity / incongruity (0-3)Estimated step-off / irregularityStructural burden (0-4)Quantitative classConfidence
Right tibiofemoral lateral3333approximately 2-4 mm irregular depressed contour / incongruity4.0End-stage lateral post-traumatic OA patternHigh
Right tibiofemoralmedial2111no major step-off1.8Secondary degenerative involvementModerate
Right patellofemoral110-10no major collapse seen0.9Mild degenerative involvementModerate
Left tibiofemoral medial110-10none1.1Mild primary OA patternModerate
Left tibiofemoral lateral0000none0.1Preserved compartmentHigh
Left patellofemoral0-10-100none0.3Minimal / early changeLow-moderate
2B. Knee-level global indices
KneeGlobal KL gradeAhlbäck estimateDominant compartmentDominant patternHardware influenceGlobal burden (0-4)Confidence
Right43Lateral tibiofemoralSevere post-traumatic OA with chronic plateau deformityYes3.4-3.7High
Left20-1Medial tibiofemoralMild primary degenerative OANo0.8-1.1Moderate
2C. Structural lesion inventory
Feature domainRight kneeLeft knee
Major joint-space collapseLateral compartment severe / near bone-on-boneNone
Secondary joint-space lossMedial mild-moderate; patellofemoral mildMedial mild
Marginal osteophyte burdenModerate-marked, lateral-predominantMild
Subchondral sclerosis burdenMarked lateral, mild medialMinimal
Articular contour remodelingMarked lateral plateau post-traumatic remodelingNone significant
Bone attrition / depressed plateau morphologyPresent, chronicAbsent
Aggressive lysis / destructive patternNot seenNot seen
Large effusion markerNot definiteNot seen
Hardware failure markerNot seenNot applicable
2D. Hardware / post-traumatic structural block
ParameterRight knee
Fixation constructProximal tibial plate-and-screw fixation
Hardware integrityNo gross breakage identified on current radiographs
Perihardware lucencyNo definite loosening pattern seen on provided views
Fracture-healing statusChronic healed tibial plateau fracture morphology
Residual structural consequencePersistent lateral plateau deformity with articular incongruity and secondary OA concentration
2E. Inter-side structural ratios
MetricValue
Right:left global burden ratioapproximately 3.3:1 to 4.1:1
Right:left lateral compartment burden ratioMarkedly asymmetric; effectively end-stage vs preserved
Right:left medial compartment burden ratioapproximately 1.6:1
Right:left patellofemoral burden ratioapproximately 3:1

3. Temporal Stability Analysis

Single-timepoint limitations apply. True longitudinal deltas are not computable and remain suppressed rather than inferred.

FieldStatus
Prior date(s)Not available
Delta matrixNot computable
Temporal stability scoreNot computable
Structural drift vectorNot computable
Longitudinal symmetry trendNot computable
Baseline registry anchorEstablished at current study date

Baseline-only temporal anchor table

DomainBaseline value
Dataset typeSingle / baseline-only
Progression stateNot assessable from current dataset alone
Future comparison anchorCurrent study should serve as baseline for subsequent serial knee imaging
Longitudinal cautionAny future interval claim should be compartment-matched against the current right lateral plateau and bilateral medial compartments separately

4. Age-Adjusted Reference Values

4A. Age-context overlay (XR-derived; research estimate)
ParameterRight kneeLeft knee
Age-expected degenerative burden at 84 yearsExceededMildly within / slightly above expected late-life range
Structural burden percentile (XR-only estimate)Greater than 95th percentile for age-matched degenerative burden because of major post-traumatic distortionApproximately 60th-75th percentile
Pattern attributionAge alone insufficient to explain severity;trauma-dominant structural accelerationAge-compatible mild medialOA
Bone-quality contextReduced mineralization likely contributes to remodeling vulnerabilitySimilar systemic context, lower local structural expression
4B. Age-adjusted burden summary
MetricEstimate
Age-adjusted right knee excess burden scoreHigh
Age-adjusted left knee excess burden scoreLow
Age-adjusted asymmetry excessMarked
Age-adjusted bilateral OA symmetry expectationViolated by right post-traumatic concentration

5. Symmetry Metrics

5A. Bilateral compartment symmetry matrix

Symmetry index convention1.00 = near-symmetric0.00 = maximally asymmetric

CompartmentLeft burdenRight burdenSymmetry indexAsymmetry classDominant side
Medial tibiofemoral1.11.80.61Mild-moderate asymmetryRight
Lateral tibiofemoral0.14.00.02-0.08Extreme asymmetryRight
Patellofemoral0.30.90.57Mild-moderate asymmetryRight
Whole-knee composite0.8-1.13.4-3.70.22-0.28Marked global asymmetryRight
5B. Normalized asymmetry interpretation
MetricValue / interpretation
Global bilateral knee symmetry classLow symmetry
Dominance patternRight-dominant structural burden
Asymmetry driverRight lateral tibiofemoral collapse plus post-traumatic plateau remodeling
Secondary asymmetryRight medial compartment
Minor asymmetryPatellofemoral
Bilateral degenerative concordancePartial only; shared mild medial OA but not shared severity architecture
5C. Text-mode symmetry heatmap
RegionHeat status
Right lateral tibiofemoralRED
Right medial tibiofemoralORANGE
Right patellofemoralYELLOW
Left medial tibiofemoralYELLOW
Left lateral tibiofemoralGREEN
Left patellofemoralGREEN

6. DEXA-Radiograph Correlation Summary

6A. Availability table
FieldStatus
DEXA datasetNot attached
BADANot directly computable
Delta BMDnormNot computable
DRINot directly computable
Cross-modal fusionNot activated
Proxy-only XR bone-quality modelingActivated
6B. XR-proxy bone-health estimates (research-only; moderate uncertainty)
Proxy metricEstimateInterpretation
Radiographic bone-quality deviationapproximately 0.44-0.52Mild-moderate deviation from robust bone appearance
Mineralization integrity proxyapproximately 0.58-0.64Borderline / mildly impaired XR-only proxy range
Composite bone-integrity proxyapproximately 0.56-0.62Borderline-to-at-risk XR-only estimate
Proxy uncertaintyModerateKnee radiographs only; no direct densitometry
Bone-age deviationNot reliably computable without densitometric input
6C. Cross-modal narrative summary
  • Current images show probable generalized osteopenic background, but the dataset is insufficient for true densitometric quantification.
  • Structural damage concentration in the right knee is driven predominantly by post-traumatic articular remodeling and compartment overload, not by diffuse bone-loss pattern alone.
  • If DEXA is later attached, the current study is suitable as a structural baseline for subsequent densitometric-structural concordance analysis.

7. Composite Structural Metrics

7A. Core composite outputs (XR-only / single-timepoint adapted)
Composite metricValueClass / interpretation
Composite Structural Stability Index0.39-0.46Low structural stability reserve
Composite Disease-Trajectory Index0.76-0.84Class IV / advanced structural burden class
Stability score0.30-0.38Low
Discrepancy classType DAsymmetry-driven inconsistency
Region-weighted burden score0.79High burden dominated by right lateral compartment
Structural phenotype profileOA / post-traumatic / lateral-predominant / unilateral-heavyResearch phenotype only
7B. Composite driver matrix
DriverWeight in this caseNotes
Structural collapse / JSNVery highMain dominant feature
Articular deformityVery highChronic plateau distortion materially increases burden
Osteophyte burdenModerateSupports KL 4 but is not the sole driver
SclerosisModerateLateral compartment concentrated
Bilateral asymmetryVery highMajor composite penalty
Densitometric contributionLow-moderate / proxy onlyNo DEXA
Temporal contributionNot availableNo prior
Inflammatory contributionNot activatedCurrent morphology is not inflammatory-dominant
7C. Endpoint-style research summary
Endpoint fieldStatus
Stability bandLow stability
Damage classAdvanced
Drift gateNot computed in true temporal sense (single timepoint)
Surgery anchor (imaging-only structural anchor)Positive
Flare anchorNot computable from imaging alone
Escalation anchorNot computable from imaging alone
Phenotype risk profileOA-post-traumatic dominant

8. QA / Reliability Indicators

8A. Acquisition / adequacy / provenance
QA fieldStatus
Projection adequacyAdequate for weight-bearing compartment analysis and hardware review
Weight-bearing data presentYes
Bilateral comparison availableYes
Laterality confidenceHigh
Dataset completeness for knee scoringHigh
DICOM-led confidenceNot available from current upload context
Source provenanceImage bundle adequate; research extraction based on visible projections only
8B. Quantitative reliability summary
MetricEstimate / status
Confidence tier (global)Moderate-high
Confidence weighting summaryHigh for right lateral OA severity; moderate for medial and patellofemoral fine grading; moderate for bone-quality proxy
Quantitative concordance indexNot formally paired with human baseline in this session; external concordance not computed
Missingness logPresent
Missingness reasonNo prior serial study; no DEXA; no MRI / CT; no external AI input; no paired human annotation grid
8C. Missing or suppressed fields
Field groupReason suppressed
True temporal deltasNo prior matched study
Densitometric linkage metricsNo DEXA
Cross-modal fusionNo MRI / CT / DEXA fusion dataset
External AI provenanceNone attached
Human override provenanceNone invoked in this addendum
Formal QCL agreement indexNo paired human scoring baseline supplied in-session
8D. Structured QA flags (human-readable)
QA itemStatus
Hard-block morphology completeness issueNo
Table orphaning riskNo
Token-scrub conflict in visible addendum textNo
Experimental envelope activeYes
Missingness recordedYes
Baseline-only temporal stateYes
Experimental Research Addendum

9. Prototype Composite Metrics

9A. Biomechanical stress / cartilage-load layer (XR-derived research estimates)
MetricRight kneeLeft kneeInterpretation
Load vector amplitude0.88-0.930.28-0.40Markedly concentrated load on right
Stress gradient strength0.80-0.870.20-0.32Strong right compartment stress gradient
Osteochondral transition stress index0.70-0.790.12-0.24Advanced right transition-zone stress
Joint-load asymmetry index0.78-0.86High inter-side imbalance
Mechanical drift-coupling indexBaseline-only / not truly temporalSingle-timepoint limitation
Mechanical degeneration amplitude0.81-0.890.18-0.28Right severe, left mild
Mechanical degeneration class41Severe unilateral mechanical degeneration vs mild contralateral degeneration
Load stability index0.24-0.340.78-0.86Unstable right, relatively preserved left
9B. Plateau incongruity and collapse-focused prototype metrics
Prototype metricValueInterpretation
Lateral plateau incongruity index0.68-0.77High
Unilateral load concentration score0.84Marked right-sided concentration
Cross-compartment discordance score0.74Advanced lateral vs milder medial / patellofemoral mismatch
Structural dominance ratioapproximately 3.5:1Right-dominant disease geometry
Post-traumatic remodeling amplitude0.79High chronic remodeling signal
9C. Visual analytics surrogate (text-mode only)
Visual metricEstimate / status
Heat index (right lateral compartment)approximately 0.90
Heat index (left medial compartment)approximately 0.32
Drift scoreNot applicable without serial study
Overlay concordanceNot formally computed without validated segmentation overlay
Drift confidence indexNot applicable
Attention-weight peak zoneRight lateral tibiofemoral compartment

10. Extended Bone-Health Models

10A. XR-only mineralization / metabolic proxy layer
MetricValueInterpretation
Bone-quality deviation vector0.44-0.52Mild-moderate global deviation
Mineralization integrity proxy0.58-0.64Borderline / mildly impaired
Composite mineral integrity classBorderline-to-at-riskXR-only proxy
Proxy confidenceModerateNo DEXA attached
Metabolic-structural concordancePartialOsteopenic background present, but focal post-traumatic load dominates phenotype
10B. Extended divergence estimate
Divergence metricEstimate
Cortical-trabecular divergence proxy1-2
Structural-mineral mismatchModerate
Dominant source of mismatchFocal right post-traumatic remodeling exceeds systemic bone-quality signal

11. Infection / Oncologic Advanced Operators

11A. Infection-oriented imaging vector
FieldStatus
Aggressive periosteal reactionNot seen
Soft-tissue gas patternNot seen
Rapid destructive septic-type patternNot seen on current radiographs
Hardware infection imaging concernLow on radiograph alone
Infection-oriented advanced operatorNot activated beyond low baseline concern
11B. Oncologic / destructive-pattern vector
FieldStatus
Aggressive permeative lysisNot seen
Focal destructive mass-like osseous changeNot seen
Pathologic fracture patternNot suggested
Oncologic concern vectorLow

12. Advanced Symmetry Maps

Advanced symmetry fieldValue / status
Higher-order asymmetry amplitudeHigh
Dominant asymmetry axisLateral compartment / post-traumatic axis
Bilateral load ratioMarkedly right-dominant
Symmetry penalty to composite scoreHigh
Potential future normalizationUnassessable without serial study

13. Genetic / Developmental Modulation

FieldStatus
Developmental layerNot applicable (adult case)
Pediatric normalizationNot applicable
Genetic modulation amplitudeNot meaningfully activatable from current dataset
Variant-sensitive morphology flagNot supported by current images
Genetic / developmental modulation blockSuppressed / non-informative

14. External AI Integration Hooks

FieldStatus
External AI sourceNone attached
External confidence weightNot used
External timestampN/A
Human override provenanceNot used
Fusion with external modelNot activated

15. QA & Data Integrity Extensions

15A. Research completeness matrix
Module groupStatus
Quantitative structural extractionComplete for current XR scope
Bilateral symmetry layerSubstantially complete
Temporal engineBaseline-only
Densitometric linkageProxy-only
Biomechanical stress layerActive
Visual analytics layerPartially activatable in text-mode surrogate
Infection / oncologic advanced layerScreened; low concern
Genetic / developmental layerNot applicable / low utility
External AI provenanceNot present
15B. Data-integrity notes
ItemStatus
Region omission detectedNo
Projection mismatch blocking scoringNo
Arthroplasty exclusion issueNo arthroplasty-related suppression required
Hardware-related interpretive limitationPresent but not dominant enough to invalidate compartment scoring
Missingness documentedYes
Research-tier integrity preservedYes

16. High-density analytic summary

  • Dominant structural event: severe right lateral tibiofemoral post-traumatic OA with chronic plateau incongruity, maximal burden concentration, and marked inter-side asymmetry.
  • Secondary structural event: mild-moderate right medial degenerative involvement.
  • Contralateral state: mild left medial OA, otherwise relatively preserved left knee.
  • Bone-health context: probable osteopenic background, but no direct densitometric quantification available.
  • Composite research profile: high-burden, asymmetry-dominant, load-concentrated unilateral advanced OA geometry with positive structural surgery anchor and suppressed true temporal / drift computations because no prior is available.
  • Best showcase layers activated here: quantitative knee scoring, compartmental burden matrix, bilateral symmetry analytics, XR-proxy bone-health modeling, composite burden / stability metrics, biomechanics / cartilage-load analytics, visual heat surrogate, and QA-integrity registry-style completeness.
PDFOpen analytic addendum

Radiographs · all views

8 views · click to enlarge · grayscale demo previews · full-resolution by request
Bilateral knees - PA flexion (weight-bearing)
Bilateral PA flexion
Bilateral knees - AP standing (weight-bearing)
Bilateral AP standing
Right knee - AP
Right AP
Right knee - oblique
Right Oblique
Right knee - lateral
Right Lateral
Left knee - AP
Left AP
Left knee - oblique
Left Oblique
Left knee - lateral
Left Lateral
PDFOpen image compilation (higher-resolution PDF)Full-resolution de-identified images available by request.

How case complexity scales

FoundationalThis case

Single date · one modality · structural read on a clean baseline.

Longitudinal

Multiple timepoints · interval deltas, drift vectors and temporal stability become computable.

Multi-modality

More than one modality (e.g. XR + DEXA / MRI / US) · cross-modal fusion and densitometric-structural concordance.

Each tier contributes and compounds structural context; tiers describe scope of input, not interpretive quality.

Olga Goodman, MD

Rheumatologist and creator of RheumaView™.